Two Worst-Case Vaccine Scenarios are in Play

Two Worst-Case Vaccine Scenarios are in Play. By Raymond Wolfe.

Earlier this week, the CDC updated guidance to state that Americans should once again mask up indoors if they are in areas of “high” or “substantial” virus transmission, even after receiving COVID-19 vaccines. “Emerging evidence suggests that fully vaccinated persons who do become infected with the Delta variant are at risk for transmitting it to others,” the agency’s guidelines now say, citing “unpublished data,” some of which was released Friday. …

Dr. Malone notably claims to have been the chief inventor of mRNA technology and mRNA and DNA innovations while working with the Salk Institute in the 1980s. Both the Pfizer and Moderna COVID-19 vaccines rely on mRNA technology. Malone is also a licensed physician who received his medical training at Northwestern University, Harvard University medical school, and UC Davis. …

“We’ve seen a progression of increasingly desperate and abrupt rollouts of information, beginning with Pfizer’s alert a couple of weeks ago that they think we were going to need to have a booster after six months, and Fauci reprimanding them, and then the government flip-flopping and saying that we were going to have to have boosters for Pfizer recipients after six months in elderly and immunocompromised, and then the bomb dropped last night,” Malone said. …

Antibody dependent enhancement (ADE)

Based on statements in the report, Malone inferred that viral levels were higher in vaccinated people than in unvaccinated people. As he later explained on Twitter, this has not been resolved. …

“This is precisely what one would see if antibody dependent enhancement (ADE) was happening,” Malone said regarding higher virus levels among the vaccinated.

“What is antibody dependent enhancement? Briefly, it’s that the vaccine causes the virus to become more infectious than would happen in the absence of vaccination, would cause the virus to replicate at higher levels than in the absence of infection.” …

“This is the vaccinologist’s worst nightmare. It happened with the respiratory syncytial virus and in the ‘60s and caused more child deaths in vaccine recipients than unvaccinated. It happened with Dengvaxia, the dengue vaccine,” Malone continued.

“And it’s happened with virtually every other coronavirus vaccine development program, certainly in humans, known in history, and it’s what the vaccinologists like myself have been warning about since the outset …”

Malone said that antibody dependent enhancement seems most apparent in people injected with Pfizer’s vaccine.

“So, we now know that the Pfizer protection is waning at six months,” he said. … This suggests … the window of greatest susceptibility to antibody dependent enhancement is in this long tapering phase as the vaccine response declines.” …

“And I don’t mean to sound alarmist, but what seems to be rolling out is the worst-case scenario, where the vaccine in the waning phase is causing the virus to replicate more efficiently than it would otherwise …”

“If the data are consistent with [antibody dependent enhancement], we have to stop the vaccine campaign,” Malone stressed. “We have to pivot to expediting as much as possible drug treatments, which have been largely blocked and suppressed at the FDA level, particularly for repurposed drugs.” …

Vaccine escape and Marek’s disease

Malone said “the escape mutants that are escaping vaccine selective pressure are most likely developing in the people that have been vaccinated, not in the unvaccinated.”

From an earlier post, by Joanne Nova:

This virus appears to have the ability (like Marek’s disease) to cloak itself from our immune system and hide in protected cells. …

[Together with vaccines that do not ill the virus but just suppress symptoms, this creates] a perfect storm, where vaccinated people feel OK, but viruses hidden away within keep sending out copies that test the half-baked immune response in a holding pattern until one lucky mutant virus escapes the net. The new variant is nastier and trickier than the last one and we need to redesign a new vaccine.

Repeat, rinse, recycle a few times and we might be breeding a virus that is more easily spread and has a higher mortality rate — especially for unvaccinated people.

This process is called immune escape, and once you know where to look, it seems virologists have been warning of it (and here, and here). But not necessarily expanding on just how bad it could be. They only mention that we might have to produce a new vaccine. (Gosh, darn, won’t Big Pharma be disappointed?) …

In the last six years it’s been confirmed and accepted that vaccines played a role in creating a much nastier and deadlier form of Marek disease in chickens (MDV).

Over the last 50 years, we’ve made vaccines that stop the chickens getting cancer and dying, but don’t stop them shedding virus and infecting other chickens. Unlike most viruses MDV can sit latent “for life” and slowly churn out copies while also suppressing the immune system. So each chicken becomes a kind of slow slot machine in a game of viral poker. The chicken’s immune system holds it at bay, but sooner or later, the virus finds an escape route around the immune system, becoming more infectious, more virulent, and effectively bypassing the current vaccine.

This process started in 1970 with the first vaccine which at the time stopped 99% of Marek’s disease. The disease originally had a low mortality but after 50 years, the MDV virus has become a kind of monster, and is considered to be 100% fatal to unvaccinated chickens. For a chicken, the odds are worse than Ebola. What have we done?

The chicken industry has learned to live with Mareks disease. Unvaccinated chickens though, have not. And the industry loses $2b a year as well. Chicks are reared separately from mum and dad apparently, so they can survive long enough to get the vaccine and get protection before they risk catching the disease. Some people keep unvaccinated backyard flocks, but those chickens don’t go on holidays, or to weddings or funerals and rarely meet other chickens.

None of this translates too well to homo sapiens. Dystopia 2025?

Group-think and incompetence

Back to Karl Malone:

Malone said he is witnessing “the most florid example, to my eye, of groupthink that I’ve ever seen in my life.” …

They think the vaccines are perfectly safe. And not only they’re not perfectly safe, if this is true, that NBC reports, and the titers are higher in vaccinated than unvaccinated, that means we got the worst case type of adverse event that scares vaccinologists, all vaccinologists, which is antibody dependent enhancement.”

“They’re all in, and they seem to be unable to process this new information, and it seems to be causing cognitive dissonance and causing these people to be increasingly frantic and transparent in their chaotic messaging,” Dr. Malone continued.

Neither scenario might develop, and it might all be fine — but it might not. A dopey leadership class doesn’t seem to have caught on to the dangers yet. Suppressing the disease with anti-virals might be far safer and more effective in the long run.

hat-tip Chris D., Charles