The Virus: Vaccines Aren’t Forever

The Virus: Vaccines Aren’t Forever

by David Archibald

15 April 2021

 

Vaccines have a reputation of being good and wholesome, like motherhood. Vaccines for polio, whooping cough, measles and so on have removed the scourge of these diseases from modern life and have done it cheaply. The polio vaccine for example costs $0.10 per dose. Which means that we have come to expect too much from vaccines, perhaps.

Especially against escaped bioweapons designed to be difficult to treat. The context of that starts with a book published in 1999 by two PLA officers, Qiao Liang and Wang Xiangsui, entitled “Unrestricted Warfare”.

 

 

The authors state that “the first rule of unrestricted warfare is that there are no rules, with nothing forbidden.” This includes peacetime attacks with bioweapons. A few years pass and in 2017 PLA general Zhang Shibo went even further in his bookWar’s New High Ground, claiming that “modern biotechnology development is gradually showing strong signs characteristic of an offensive capability,” including the potential for “specific ethnic genetic attacks”. Certainly the Chicoms have gone to great lengths to collect DNA data in the United States.

Why did the Chicom bioweapons people decide to give the SARS virus some gain of function? SARS had high transmissibility and a high case fatality rate. In the Amoy Gardens outbreak in Hong Kong in April 2003, SARS was transmitted between floors in Block E via bathroom floor drains in which the water in the water trap in floor drains had dried up, aided by exhaust fans causing negative pressure. People were infected by transmission from two floors below them.

The Wuhan virus has a higher binding affinity to the ACE-2 receptor than SARS and thus has higher transmissibility. The virus got out before the Chicoms were ready to use it, but they improvised rapidly. They locked down China but allowed international flights from Wuhan to continue. Thus the first big outbreak in the West was in northern Italy because of the China-related clothing industry there. (There is a parallel with the Soviet response to Chernobyl. At the suggestion of the then Bulgarian President, the Chernobyl incident was used to generate significant anti-nuclear sentiment in the West. That effort is still bearing fruit today with Chancellor Merkel’s closure of the German nuclear power industry.)

China has put on a brave face with respect to the Wuhan virus, but internal travel beyond one’s residence area is now highly restricted with permits needed. The SARS virus was eliminated by lockdowns until the outbreak died out. Eliminating the Wuhan virus will require the same approach. The Wuhan virus has been a big ‘own goal’ for the Chicoms. It could yet destroy the country. The higher the population density, the easier it is for the virus to keep spreading.

In the meantime the Wuhan virus is mutating, creating thousands of different variants. In a recent paper entitled “The impact of viral mutations on recognition by SARS-CoV-2 specific T-cells”  is the following figure:

 

 

The figure shows the number of Wuhan virus T-cell epitope variants by week, from the beginning of 2020, with 13 epitopes followed. A total of 309,119 samples were used to generate the data behind the graph. T-cell epitopes are regions of proteins on a foreign cell that trigger a cellular immune response by T-cells. A significant increase in sites under diversifying positive selective pressure was observed around November 2020.

The significance of all this is that the virus is mutating fast enough that vaccines developed for it are likely to have relatively short periods of usefulness. Some of the vaccines create carriers who can transmit the disease asymptomatically, especially the new variants.

Control of the disease will then have to revert to anti-virals, such as ivermectin, and social isolation. There are some antiviral molecules that the virus will not be able to mutate around.

And you don’t want to get this disease. It had been thought that children were somehow immune to the Wuhan virus, but everyone gets damaged by it. Researchers at the Children’s Hospital of Philadelphia have found elevated levels of a biomarker related to blood vessel damage in children with SARS-CoV-2 infection, even if the children had minimal or no symptoms of COVID-19. They also found that a high proportion of children with SARS-CoV-2 infection met clinical and diagnostic criteria for thrombotic microangiopathy (TMA). TMA is a syndrome that involves clotting in the small blood vessels and has been identified as a potential cause for severe manifestations of COVID-19 in adults.

There is also likely to be a long term cancer burden with the Wuhan virus caused by inflammation, just as Hepatitis C results in 20% of those infected developing liver cancer in the disease progression.

 

 

With vaccines destined to lose their efficacy, it is time to revisit what cheap antiviral molecules can do. This site has compiled Wuhan virus test results. From that site, this table summarises the data from the “no side effects” molecules in that list:

A combination of these molecules is likely to be good. Ivermectin and iodine have different binding sites on viruses and so are likely to be synergistic. These things are as good as most vaccines and no virus is going to mutate around them. China’s vaccine has less than 50% efficacy by comparison.

 

David Archibald is the author of The Anticancer Garden in Australia