Melanoma Protocol II

by David Archibald

27 July 2024

 

The story so far: four years ago, a prominent Australian at the national living treasure level had a melanoma removed from his leg.

Subsequent blood tests found melanoma stem cells present, which indicated that the melanoma had metastasised and had found a new home or homes somewhere else in his body. Cancers below 3 mm in diameter can’t be imaged by PET and MRI scans, so surgical removal wasn’t an option. Resolved to live, our Treasure studied the scientific literature and formulated his own treatment protocol. That story is told here.

The protocol is based on the concept that a cancer cell relies upon six major cellular pathways to survive, and possibly another dozen subsidiary ones. The more pathways that are blocked simultaneously, the greater the chance the cancer cell will die. His protocol doesn’t leave any stone unturned in pursuing the goal of tormenting the cancer cells using as many pathways as possible. It involved taking 40 separate doses of molecules twice per day, as well as hyperbaric oxygen and vitamin C injections.

Time passes and science marches on. The protocol has evolved and following is the current iteration:

Discussion

In prescription drugs in the last few years, there has been a lot more efficacy work done on the benzimidazoles, including fenbendazole and mebendazole. This is a very promising drug class, whose efficacy approaches the heavy-duty chemo drugs but with almost no side effects. There has been convergence in anticancer protocols to include fenbendazole and its siblings in the benzimidazole class of drugs. Following are some IC50 numbers, indicating efficacy, for fenbendazole:

 

Cancer Type			Cell Line		IC50
					µg/ml
Brain			J3T		0.2
			G06-A		0.5
			SDT-3G		0.2
Breast			MCF-7		1.6
Colorectal			HCT116		1.19
			H29		0.08
			RKO		0.08
Lung			A549		0.45
			H23		0.12
			H1650		1.86
			H2228		2.33
			H1299		0.3
			H460		0.36
			H522		0.3
Skin			Bowes		0.27
			RPMI-7951		0.33
			M-14		0.42
			SK-Mel-19		0.36

 

The protocol includes 80mg per day of melatonin. This is the result of another recent scientific advance. The pineal gland produces 0.3 mg of melatonin during sleep, peaking at 4.00 am in the morning. It is now believed that mitochondria in the body produce up to 600 mg per day in response to infrared radiation, with the melatonin consumed in the same mitochondria in which it is produced. It follows that if most of the population is vitamin D deficient (for example Australians average 25 ng/ml of vitamin D when they should be at least 50 ng/ml) because we don’t get the sun exposure we evolved to expect, we are also melatonin-deficient. This is supported by the finding of the FLCCC Alliance, that melatonin is the most cost-effective treatment for alleviating the symptoms of covid. In that same survey, vitamin D was the fourth most cost-effective treatment. It is also likely to explain the melanoma mortality paradox — that office workers have a lower skin cancer incidence than outdoor workers but have a higher melanoma mortality rate than outdoor workers.

The protocol includes sources of epicatechin gallate from green tea extract, totaling 1,200 mg per day. This is well beyond the EU recommended limit of 800 mg per day, after which liver damage is possible. Fortunately the protocol also includes silymarin from milk thistle, which is protective of the liver.

In summary, the protocol includes a number of immune system stimulants, molecules that increase the production of pro-apoptotic proteins, and ones that reduce the production of anti-apoptotic proteins (the plant flavonoids) as well as supporting effects such as metformin reducing glucose availability to the cancer cells.

 

David Archibald is the author of The Anticancer Garden in Australia