Severe COVID Looks Scarily Like Old Age in The Human Brain

Severe COVID Looks Scarily Like Old Age in The Human Brain. By Carly Cassela for Science Alert.

Severe COVID-19 looks scarily like old age in the human brain, according to a postmortem analysis of 54 healthy and infected individuals.

The authors of the study say their research is the first to link COVID-19 to molecular signatures of brain aging. …

Using RNA sequencing technology on samples of the prefrontal cortex, scientists found those with severe COVID-19 showed enriched genetic expression patterns associated with aging. …

In simple terms, genes that were usually upregulated in aging, like those to do with the immune system, were also upregulated in severe COVID-19.

At the same time, genes downregulated in aging, like those to do with synaptic activity, cognition, and memory, were downregulated in severe COVID-19, too. …

Severe cases of COVID-19 are often associated with brain fog, memory loss, stroke, delirium, or coma. …

David Archibald’s dire possibilities are in play:

Every year that passes, health experts have a slightly better idea of the long-term outcomes that this global pandemic might bring. Three years in, it’s not looking good.

The findings of the current study follow on the heels of another paper, published earlier this year, that found the cognitive impact of severe COVID-19 is equivalent to about 20 years of aging.

Neuropathologist Marianna Bugiani from Amsterdam University … added that these consequences might not be clear for many more years to come. And by this time, the global community will probably be suffering from repeat COVID-19 infections. …

Suggestions:

In light of their findings, the team says people who are recovering from COVID-19 should get neurological follow-ups. …

Until experts know more, the authors say doctors and patients should focus on other risk factors for dementia that are in our control, like weight, alcohol consumption, and exercise.

Avoiding future COVID-19 infections to the best of your ability is also probably a good idea.

The failure of the Chinese attempt to keep out covid is interesting because it shows that omicron is too infectious to keep out — given that people aren’t well motivated because omicron appears almost harmless.

Still, we are left with the nagging possibility that the Chinese military researchers were creating a bioweapon, that they threw the kitchen sink at making a deceptive long-term killer, and that we are only slowly finding out how bad covid is. The Chinese leadership knew this, which is why they went so hard to keep covid out of China.