Boston lab creates a new deadly Covid strain with an 80% kill rate among mice

Boston lab creates a new deadly Covid strain with an 80% kill rate among mice. By Caitlin Tilley.

Boston University scientists were today condemned for ‘playing with fire’ after it emerged they had created a lethal new Covid strain in a laboratory.

DailyMail.com revealed the team had made a hybrid virus — combining Omicron and the original Wuhan strain — that killed 80 per cent of mice in a study. …

Scientists measured how many copies each variant caused the healthy cells to produce. They found the hybrid strain produced five times more viral particles than the original Omicron.

The scientists admit the hybrid virus is unlikely to be as deadly in humans as it was in mice. This is because the specific breed of lab mice used are very susceptible to severe Covid disease. Mice and humans also have very different immune responses to the virus. …

Gain of function research — when viruses are purposefully manipulated to be more infectious or deadly– is thought to be at the center of Covid’s origin. …

The Coronavirus pandemic has prompted a global surge in laboratories that handle dangerous viruses — despite concerns Covid may have been the result of the risky experiments.

More than 40 facilities certified as biosafety level 3 (BSL-3) or BSL-4 have either been built or have gone into construction since 2020, predominantly across Asia.

Many countries believe they were caught flat-footed by Covid and want to get ahead of the next devastating outbreak by studying pathogens that pose a threat to humans.

Experiments at these labs often involve tinkering with animal viruses to advance treatments and vaccines that could be used in a future outbreak.

But there are widespread concerns that these experiments might actually raise the risk of pandemics — something some experts believe was the case with Covid. …

Russia has set out its proposals for 15 of the maximum security labs and India is aiming for 18 BSL-3 and BSL-4 labs in total. The US is also adding a further highest level biosecurity lab to its existing 12.

Why would anyone want to mess around with dangerous viruses?